DGCR2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DGCR2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DGCR2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DGCR2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DGCR2
Entrez GeneID
9993GeneBank Accession#
DGCR2Gene Name
DGCR2
Gene Alias
DGS-C, DKFZp686I1730, IDD, KIAA0163, LAN, SEZ-12
Gene Description
DiGeorge syndrome critical region gene 2
Omim ID
600594Gene Ontology
HyperlinkGene Summary
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. [provided by RefSeq
Other Designations
integral membrane protein DGCR2
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Interactome
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Disease
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