SLC12A6 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SLC12A6 partial ORF ( NP_005126, 1 a.a. - 90 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.64
Interspecies Antigen Sequence
Mouse (78); Rat (77)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC12A6
Entrez GeneID
9990GeneBank Accession#
NM_005135Protein Accession#
NP_005126Gene Name
SLC12A6
Gene Alias
ACCPN, DKFZp434D2135, KCC3, KCC3A, KCC3B
Gene Description
solute carrier family 12 (potassium/chloride transporters), member 6
Gene Ontology
HyperlinkGene Summary
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq
Other Designations
potassium chloride cotransporter 3|potassium chloride cotransporter KCC3a-S3|solute carrier family 12, member 6
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Interactome
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Disease
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