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SLC12A6 rabbit monoclonal antibody

  • Catalog # : H00009990-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SLC12A6 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SLC12A6 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SLC12A6 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9990
  • Gene Name:
  • SLC12A6
  • Gene Alias:
  • ACCPN,DKFZp434D2135,KCC3,KCC3A,KCC3B
  • Gene Description:
  • solute carrier family 12 (potassium/chloride transporters), member 6
  • Gene Summary:
  • This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq
  • Other Designations:
  • potassium chloride cotransporter 3,potassium chloride cotransporter KCC3a-S3,solute carrier family 12, member 6
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