REC8 (pCD) 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Product Description
Transfected Cell Line
293T
Plasmid
pCMV-REC8 (pCMV) full-length
Host
Human
Theoretical MW (kDa)
62.7
Interspecies Antigen Sequence
Mouse (70); Rat (70)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-REC8L1 (pCD) antibody (H00009985-B01) by Western Blots.
SDS-PAGE Gel
REC8 transfected lysate.
Western Blot
Lane 1: REC8 transfected lysate ( 62.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — REC8
Entrez GeneID
9985GeneBank Accession#
BC004159Protein Accession#
AAH04159.1Gene Name
REC8
Gene Alias
HR21spB, MGC950, REC8L1, Rec8p
Gene Description
REC8 homolog (yeast)
Omim ID
608193Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq
Other Designations
REC8 homolog|REC8-like 1|cohesion rec8p|human homolog of rad21, S. pombe|meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family|meiotic recombination protein REC8-like 1|recombination and sister chromatid cohesion protein
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Interactome
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Disease
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