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Last updated: 2016/10/23
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NR1I3 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00009970-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human NR1I3 protein.
  • Immunogen:
  • NR1I3 (NP_001070948.1, 1 a.a. ~ 352 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of NR1I3 expression in transfected 293T cell line (H00009970-T01) by NR1I3 MaxPab polyclonal antibody.

    Lane 1: NR1I3 transfected lysate(38.72 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9970
  • Gene Name:
  • NR1I3
  • Gene Alias:
  • CAR,CAR1,MB67,MGC150433,MGC97144,MGC97209
  • Gene Description:
  • nuclear receptor subfamily 1, group I, member 3
  • Gene Summary:
  • This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032245,OTTHUMP00000032246,constitutive activator of retinoid response,constitutive active receptor,constitutive androstane receptor,orphan nuclear hormone receptor
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