TNFSF15 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: TNFSF15 transfected lysate ( 28.1 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
TNFSF15 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFSF15 full-length
Host
Human
Theoretical MW (kDa)
27.72
Interspecies Antigen Sequence
Rat (68)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFSF15 antibody (H00009966-B01) by Western Blots.
Western Blot
Lane 1: TNFSF15 transfected lysate ( 28.1 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TNFSF15 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFSF15
Entrez GeneID
9966GeneBank Accession#
NM_005118Protein Accession#
NP_005109Gene Name
TNFSF15
Gene Alias
MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A
Gene Description
tumor necrosis factor (ligand) superfamily, member 15
Omim ID
604052Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000022739|TNF ligand-related molecule 1|TNF superfamily ligand TL1A|vascular endothelial cell growth inhibitor|vascular endothelial growth inhibitor-192A
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