P2RY14 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human P2RY14 peptide using ARM Technology.
Immunogen
A synthetic peptide of human P2RY14 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human P2RY14 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — P2RY14
Entrez GeneID
9934GeneBank Accession#
P2RY14Gene Name
P2RY14
Gene Alias
GPR105, KIAA0001, P2Y14
Gene Description
purinergic receptor P2Y, G-protein coupled, 14
Omim ID
610116Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
G protein coupled receptor for UDP-glucose|G protein-coupled receptor 105|P2Y purinoceptor 14|P2Y(14) receptor|P2Y14 receptor
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Pathway
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