MRC2 monoclonal antibody (M01), clone 2D7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MRC2.
Immunogen
MRC2 (NP_006030, 105 a.a. ~ 214 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ASLGMYECDREALNLRWHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MRC2
Entrez GeneID
9902GeneBank Accession#
NM_006039Protein Accession#
NP_006030Gene Name
MRC2
Gene Alias
CD280, CLEC13E, ENDO180, FLJ35911, KIAA0709, UPARAP
Gene Description
mannose receptor, C type 2
Gene Ontology
HyperlinkGene Summary
MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007 [PubMed 17974964]).[supplied by OMIM
Other Designations
endocytic receptor (macrophage mannose receptor family)|urokinase plasminogen activator receptor-associated protein
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Interactome
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Disease
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Publication Reference
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Interleukin-1 alpha derived from ultraviolet B-exposed keratinocytes is associated with a decrease of endocytic collagen receptor Endo180.
Iwahashi H, Kawashima Y, Masaki H.
Photodermatology, Photoimmunology & Photomedicine 2019 Aug; [Epub].
Application:IF, Human, Human dermal fibroblasts .
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Interleukin-1 alpha derived from ultraviolet B-exposed keratinocytes is associated with a decrease of endocytic collagen receptor Endo180.
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