Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

POM121

Gene Alias

DKFZp586G1822, DKFZp586P2220, FLJ41820, KIAA0618, MGC3792, POM121A

Gene Description

POM121 membrane glycoprotein (rat)

Gene Ontology

Gene Summary

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq

Other Designations

OTTHUMP00000160224|P145|nuclear envelope pore membrane protein POM 121|nuclear pore membrane protein 121|nuclear pore membrane protein 121 kDa