SETDB1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SETDB1 full-length
Host
Human
Theoretical MW (kDa)
142.01
Interspecies Antigen Sequence
Mouse (90); Rat (90)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SETDB1 antibody (H00009869-B01) by Western Blots.
SDS-PAGE Gel
SETDB1 transfected lysate.
Western Blot
Lane 1: SETDB1 transfected lysate ( 142.01 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SETDB1
Entrez GeneID
9869GeneBank Accession#
NM_012432.2Protein Accession#
NP_036564.2Gene Name
SETDB1
Gene Alias
ESET, KG1T, KIAA0067, KMT1E
Gene Description
SET domain, bifurcated 1
Omim ID
604396Gene Ontology
HyperlinkGene Summary
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described
Other Designations
ERG-associated protein with a SET domain, ESET
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Interactome
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Pathway
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Disease
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