SETDB1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SETDB1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SETDB1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SETDB1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SETDB1
Entrez GeneID
9869GeneBank Accession#
SETDB1Gene Name
SETDB1
Gene Alias
ESET, KG1T, KIAA0067, KMT1E
Gene Description
SET domain, bifurcated 1
Omim ID
604396Gene Ontology
HyperlinkGene Summary
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described
Other Designations
ERG-associated protein with a SET domain, ESET
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Interactome
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