TOMM70A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TOMM70A protein.
Immunogen
TOMM70A (NP_055635, 1 a.a. ~ 608 a.a) full-length human protein.
Sequence
MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TOMM70A MaxPab polyclonal antibody. Western Blot analysis of TOMM70A expression in human liver.Western Blot (Cell lysate)
TOMM70A MaxPab polyclonal antibody. Western Blot analysis of TOMM70A expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of TOMM70A expression in transfected 293T cell line by TOMM70A MaxPab polyclonal antibody.
Lane 1: TOMM70A transfected lysate(66.88 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to TOMM70A on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — TOMM70A
Entrez GeneID
9868GeneBank Accession#
NM_014820Protein Accession#
NP_055635Gene Name
TOMM70A
Gene Alias
FLJ90470
Gene Description
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
Omim ID
606081Gene Ontology
HyperlinkGene Summary
The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. See TIM17A (MIM 605057).[supplied by OMIM
Other Designations
translocase of outer mitochondrial membrane 70 homolog A
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Interactome
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Disease
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Publication Reference
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Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
Li Xuan Tan, Colin J Germer, Thushara Thamban, Nilsa La Cunza, Aparna Lakkaraju.
Current Biology : CB 2023 Sep; 33(18):3805.
Application:IF, Mouse, Mouse RPE.
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TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer.
Filadi R, Leal NS, Schreiner B, Rossi A, Dentoni G, Pinho CM, Wiehager B, Cieri D, Cali T, Pizzo P, Ankarcrona M.
Current Biology : CB 2018 Feb; 28(3):369.
Application:WB, Human, Mouse , HEK 293 cells, MEFs, Mouse brain.
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Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
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