MED24 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MED24 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MED24 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MED24 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MED24
Entrez GeneID
9862GeneBank Accession#
MED24Gene Name
MED24
Gene Alias
ARC100, CRSP100, CRSP4, DRIP100, KIAA0130, MGC8748, THRAP4, TRAP100
Gene Description
mediator complex subunit 24
Omim ID
607000Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000164458|OTTHUMP00000164460|activator-recruited cofactor 100 kDa component|cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa|mediator of RNA polymerase II transcription, subunit 24 homolog|thyroid hormone receptor associate
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Interactome
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