GAB2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
GAB2 transfected lysate.
Western Blot
Lane 1: GAB2 transfected lysate ( 74.50 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GAB2 full-length
Host
Human
Theoretical MW (kDa)
74.5
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GAB2 antibody (H00009846-D01P) by Western Blots.
SDS-PAGE Gel
GAB2 transfected lysate.
Western Blot
Lane 1: GAB2 transfected lysate ( 74.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GAB2
Entrez GeneID
9846GeneBank Accession#
NM_080491Protein Accession#
NP_536739.1Gene Name
GAB2
Gene Alias
KIAA0571
Gene Description
GRB2-associated binding protein 2
Omim ID
606203Gene Ontology
HyperlinkGene Summary
This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
Grb2-associated binder 2
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Interactome
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Pathway
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Disease
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