ELMO1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ELMO1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ELMO1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ELMO1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ELMO1
Entrez GeneID
9844GeneBank Accession#
ELMO1Gene Name
ELMO1
Gene Alias
CED-12, CED12, ELMO-1, KIAA0281, MGC126406
Gene Description
engulfment and cell motility 1
Omim ID
606420Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
ced-12 homolog 1
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Interactome
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Pathway
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Disease
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