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ARHGEF11 Pre-design Chimera RNAi

  • Catalog # : H00009826-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_014784
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9826
  • Gene Name:
  • ARHGEF11
  • Gene Alias:
  • DKFZp667F1223,GTRAP48,KIAA0380,PDZ-RHOGEF
  • Gene Description:
  • Rho guanine nucleotide exchange factor (GEF) 11
  • Gene Summary:
  • Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000038716,OTTHUMP00000038717,Rho guanine exchange factor (GEF) 11,RhoA-specific guanine nucleotide exchange factor,RhoGEF glutamate transport modulator,glutamate transporter EAAT4-associated protein 48
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