ARHGEF11 monoclonal antibody (M02), clone 2F4
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More Files
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Western Blot (Tissue lysate)
ARHGEF11 monoclonal antibody (M02), clone 2F4. Western Blot analysis of ARHGEF11 expression in human colon.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ARHGEF11 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.63 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ARHGEF11.
Immunogen
ARHGEF11 (AAH57394, 651 a.a. ~ 750 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEATRLHQSASSSTSSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDTLLPHLLEDDLGQLSDLEPE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (93)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ARHGEF11 monoclonal antibody (M02), clone 2F4. Western Blot analysis of ARHGEF11 expression in human colon.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ARHGEF11 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — ARHGEF11
Entrez GeneID
9826GeneBank Accession#
BC057394Protein Accession#
AAH57394Gene Name
ARHGEF11
Gene Alias
DKFZp667F1223, GTRAP48, KIAA0380, PDZ-RHOGEF
Gene Description
Rho guanine nucleotide exchange factor (GEF) 11
Omim ID
605708Gene Ontology
HyperlinkGene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000038716|OTTHUMP00000038717|Rho guanine exchange factor (GEF) 11|RhoA-specific guanine nucleotide exchange factor|RhoGEF glutamate transport modulator|glutamate transporter EAAT4-associated protein 48
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Interactome
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Disease
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