MAML1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human MAML1 partial ORF ( NP_055572, 655 a.a. - 754 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (86); Rat (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAML1
Entrez GeneID
9794GeneBank Accession#
NM_014757Protein Accession#
NP_055572Gene Name
MAML1
Gene Alias
KIAA0200, Mam-1, Mam1
Gene Description
mastermind-like 1 (Drosophila)
Omim ID
605424Gene Ontology
HyperlinkGene Summary
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq
Other Designations
mastermind homolog|mastermind-like 1
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Interactome
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Pathway
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Disease
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