RAPGEF5 monoclonal antibody (M09), clone 2E4
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More Files
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Western Blot (Cell lysate)
RAPGEF5 monoclonal antibody (M09), clone 2E4. Western Blot analysis of RAPGEF5 expression in Hela S3 NE ( Cat # L013V3 ).
Western Blot detection against Immunogen (74.58 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant RAPGEF5.
Immunogen
RAPGEF5 (AAH39203, 1 a.a. ~ 444 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGSSRLRVFDPHLERKDSAAALSDRELPLPTFDVPYFKYIDEEDEDDEWSSRSQSSTEDDSVDSLLSDRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPRRKRKVLHLVSQWIALYKDWLPEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTETEEIFCHVYITEHSYVSVKAKVSSIAQEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFRKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFVPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGDLSPKEHQELKSYVNHLYVIDSQQALFELSHRIEPRV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (74.58 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
RAPGEF5 monoclonal antibody (M09), clone 2E4. Western Blot analysis of RAPGEF5 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — RAPGEF5
Entrez GeneID
9771GeneBank Accession#
BC039203Protein Accession#
AAH39203Gene Name
RAPGEF5
Gene Alias
GFR, KIAA0277, MR-GEF, REPAC
Gene Description
Rap guanine nucleotide exchange factor (GEF) 5
Omim ID
609527Gene Ontology
HyperlinkGene Summary
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM
Other Designations
M-Ras-regulated GEF|guanine nucleotide exchange factor for Rap1
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Interactome
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Disease
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