HDAC4 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of HDAC4 transfected lysate using rabbit polyclonal anti-HDAC4 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-HDAC4.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of HDAC4 transfected lysate using rabbit polyclonal anti-HDAC4 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-HDAC4.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-HDAC4 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-HDAC4 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — HDAC4
Entrez GeneID
9759Gene Name
HDAC4
Gene Alias
HA6116, HD4, HDAC-A, HDACA, KIAA0288
Gene Description
histone deacetylase 4
Omim ID
605314Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq
Other Designations
histone deacetylase A
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Interactome
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Disease
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