RICS DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RICS DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MPPKVLSTWWRGKHGFQVGLFPGHCVELINQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLLPHFSARTELIVPFPLRLLRKQFTPPLLGPMSPLNPLVQITVCISI
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — RICS
Entrez GeneID
9743GeneBank Accession#
BC000277Protein Accession#
AAH00277Gene Name
RICS
Gene Alias
GC-GAP, GRIT, KIAA0712, MGC1892, p200RhoGAP, p250GAP
Gene Description
Rho GTPase-activating protein
Omim ID
608541Gene Ontology
HyperlinkGene Summary
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM
Other Designations
GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein
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Interactome
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Disease
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