RICS (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human RICS full-length ORF ( AAH00277, 1 a.a. - 322 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPPKVLSTWWRGKHGFQVGLFPGHCVELINQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLLPHFSARTELIVPFPLRLLRKQFTPPLLGPMSPLNPLVQITVCISI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
61.16
Interspecies Antigen Sequence
Mouse (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RICS
Entrez GeneID
9743GeneBank Accession#
BC000277Protein Accession#
AAH00277Gene Name
RICS
Gene Alias
GC-GAP, GRIT, KIAA0712, MGC1892, p200RhoGAP, p250GAP
Gene Description
Rho GTPase-activating protein
Omim ID
608541Gene Ontology
HyperlinkGene Summary
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM
Other Designations
GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein
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Interactome
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Disease
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