NOS1AP 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NOS1AP full-length
Host
Human
Theoretical MW (kDa)
56.1
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NOS1AP antibody (H00009722-B01P) by Western Blots.
SDS-PAGE Gel
NOS1AP transfected lysate.
Western Blot
Lane 1: NOS1AP transfected lysate ( 56.10 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NOS1AP
Entrez GeneID
9722GeneBank Accession#
NM_014697Protein Accession#
NP_055512.1Gene Name
NOS1AP
Gene Alias
6330408P19Rik, CAPON, MGC138500
Gene Description
nitric oxide synthase 1 (neuronal) adaptor protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON)|OTTHUMP00000025714|ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain
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Interactome
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Disease
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