NOS1AP monoclonal antibody (M02), clone 3B11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NOS1AP.
Immunogen
NOS1AP (NP_055512.1, 99 a.a. ~ 202 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NOS1AP is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — NOS1AP
Entrez GeneID
9722GeneBank Accession#
NM_014697Protein Accession#
NP_055512.1Gene Name
NOS1AP
Gene Alias
6330408P19Rik, CAPON, MGC138500
Gene Description
nitric oxide synthase 1 (neuronal) adaptor protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON)|OTTHUMP00000025714|ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain
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Interactome
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Disease
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