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Last updated: 2016/12/4

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NOS1AP rabbit monoclonal antibody

  • Catalog # : H00009722-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NOS1AP peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NOS1AP is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NOS1AP peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9722
  • Gene Name:
  • NOS1AP
  • Gene Alias:
  • 6330408P19Rik,CAPON,MGC138500
  • Gene Description:
  • nitric oxide synthase 1 (neuronal) adaptor protein
  • Gene Summary:
  • This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON),OTTHUMP00000025714,ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain
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