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RAPGEF2 Pre-design Chimera RNAi

  • Catalog # : H00009693-R02
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  • Specification
  • Product Description:
  • PREDICTED: Homo sapiens Rap guanine nucleotide exchange factor (GEF) 2 (RAPGEF2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • XM_376350
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9693
  • Gene Name:
  • RAPGEF2
  • Gene Alias:
  • CNrasGEF,NRAPGEP,PDZ-GEF1,PDZGEF1,RA-GEF,Rap-GEP
  • Gene Description:
  • Rap guanine nucleotide exchange factor (GEF) 2
  • Gene Summary:
  • Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM
  • Other Designations:
  • PDZ domain containing guanine nucleotide exchange factor (GEF) 1,RA(Ras/Rap1A-associating)-GEF,Rap guanine nucleotide exchange factor 2
  • Gene Pathway
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