SOCS5 monoclonal antibody (M01), clone 2D1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SOCS5.
Immunogen
SOCS5 (AAH32862, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLAR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SOCS5 monoclonal antibody (M01), clone 2D1 Western Blot analysis of SOCS5 expression in HepG2 ( Cat # L019V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SOCS5 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SOCS5 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — SOCS5
Entrez GeneID
9655GeneBank Accession#
BC032862Protein Accession#
AAH32862Gene Name
SOCS5
Gene Alias
CIS6, CISH6, Cish5, KIAA0671, SOCS-5
Gene Description
suppressor of cytokine signaling 5
Omim ID
607094Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq
Other Designations
cytokine-inducible SH2 protein 6
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Interactome
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