HS2ST1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HS2ST1 full-length
Host
Human
Theoretical MW (kDa)
26.8
Interspecies Antigen Sequence
Mouse (96); Rat (97)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HS2ST1 antibody (H00009653-B01P) by Western Blots.
SDS-PAGE Gel
HS2ST1 transfected lysate.
Western Blot
Lane 1: HS2ST1 transfected lysate ( 26.80 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HS2ST1
Entrez GeneID
9653GeneBank Accession#
BC025990.1Protein Accession#
AAH25990.1Gene Name
HS2ST1
Gene Alias
FLJ11317, KIAA0448, MGC131986, dJ604K5.2
Gene Description
heparan sulfate 2-O-sulfotransferase 1
Omim ID
604844Gene Ontology
HyperlinkGene Summary
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011908
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Interactome
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Pathway
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Disease
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