PPM1F (Human) IP-WB Antibody Pair

Catalog # H00009647-PW2

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Size:1 Set
Price: USD $ 607.00
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Immunoprecipitation of PPM1F transfected lysate using mouse monoclonal anti-PPM1F and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-PPM1F.

  • Specification

    Product Description

    This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (79); Rat (79)

    Quality Control Testing

    Immunoprecipitation-Western Blot (IP-WB)

    Immunoprecipitation of PPM1F transfected lysate using mouse monoclonal anti-PPM1F and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-PPM1F.

    Supplied Product

    Antibody pair set content:
    1. Antibody pair for IP: mouse monoclonal anti-PPM1F (300 ug)
    2. Antibody pair for WB: rabbit polyclonal anti-PPM1F (50 ul)

    Storage Instruction

    Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

  • Applications

    Immunoprecipitation-Western Blot

  • Gene Info — PPM1F

    Entrez GeneID

    9647

    Gene Name

    PPM1F

    Gene Alias

    CaMKPase, FEM-2, KIAA0015, POPX2, hFEM-2

    Gene Description

    protein phosphatase 1F (PP2C domain containing)

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq

    Other Designations

    Ca(2+)/calmodulin-dependent protein kinase phosphatase|CaM-kinase phosphatase|PP2C phosphatase|partner of PIX 2|protein phosphatase 1F

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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