FEZ1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FEZ1 full-length
Host
Human
Theoretical MW (kDa)
43.23
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FEZ1 antibody (H00009638-B01) by Western Blots.
SDS-PAGE Gel
FEZ1 transfected lysate
Western Blot
Lane 1: FEZ1 transfected lysate ( 43.23 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FEZ1
Entrez GeneID
9638GeneBank Accession#
BC009545Protein Accession#
AAH09545Gene Name
FEZ1
Gene Alias
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Gene Description
fasciculation and elongation protein zeta 1 (zygin I)
Omim ID
604825Gene Ontology
HyperlinkGene Summary
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq
Other Designations
zygin 1
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Interactome
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Disease
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