CLCA2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CLCA2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CLCA2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CLCA2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CLCA2
Entrez GeneID
9635GeneBank Accession#
CLCA2Gene Name
CLCA2
Gene Alias
CACC, CACC3, CLCRG2, CaCC-3, FLJ97885
Gene Description
chloride channel regulator 2
Omim ID
604003Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. [provided by RefSeq
Other Designations
CLCA family member 2, chloride channel regulator|OTTHUMP00000011911|calcium-activated chloride channel protein 3|calcium-activated chloride channel-2|chloride channel, calcium activated, family member 2
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