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CLCA2 rabbit monoclonal antibody

  • Catalog # : H00009635-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CLCA2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CLCA2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CLCA2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9635
  • GeneBank Accession#:
  • CLCA2
  • Gene Name:
  • CLCA2
  • Gene Alias:
  • CACC,CACC3,CLCRG2,CaCC-3,FLJ97885
  • Gene Description:
  • chloride channel regulator 2
  • Gene Summary:
  • The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. [provided by RefSeq
  • Other Designations:
  • CLCA family member 2, chloride channel regulator,OTTHUMP00000011911,calcium-activated chloride channel protein 3,calcium-activated chloride channel-2,chloride channel, calcium activated, family member 2
  • Gene Pathway
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