SNCAIP monoclonal antibody (M01), clone 2A8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SNCAIP.
Immunogen
SNCAIP (NP_005451, 206 a.a. ~ 309 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (86)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.18 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SNCAIP is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — SNCAIP
Entrez GeneID
9627GeneBank Accession#
NM_005460Protein Accession#
NP_005451Gene Name
SNCAIP
Gene Alias
MGC39814, SYPH1
Gene Description
synuclein, alpha interacting protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but their full-length nature has yet to be determined. [provided by RefSeq
Other Designations
synphilin|synphilin-1|synuclein alpha interacting protein
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Interactome
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Disease
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