KLK4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KLK4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human KLK4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KLK4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KLK4
Entrez GeneID
9622GeneBank Accession#
KLK4Gene Name
KLK4
Gene Alias
ARM1, EMSP, EMSP1, KLK-L1, MGC116827, MGC116828, PROSTASE, PRSS17, PSTS
Gene Description
kallikrein-related peptidase 4
Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
androgen-regulated message 1|enamel matrix serine protease 1|kallikrein 4 (prostase, enamel matrix, prostate)|kallikrein-like protein 1|protease, serine, 17
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