NCOR1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant NCOR1.
Immunogen
NCOR1 (NP_006302, 2341 a.a. ~ 2440 a.a) partial recombinant protein with GST tag.
Sequence
GQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NCOR1
Entrez GeneID
9611GeneBank Accession#
NM_006311Protein Accession#
NP_006302Gene Name
NCOR1
Gene Alias
KIAA1047, MGC104216, N-CoR, TRAC1, hCIT529I10, hN-CoR
Gene Description
nuclear receptor co-repressor 1
Omim ID
600849Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. [provided by RefSeq
Other Designations
thyroid hormone- and retinoic acid receptor-associated corepressor 1
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Interactome
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Disease
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