TP53I3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: TP53I3 transfected lysate ( 35.5 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
TP53I3 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TP53I3 full-length
Host
Human
Theoretical MW (kDa)
36.63
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TP53I3 antibody (H00009540-B02) by Western Blots.
Western Blot
Lane 1: TP53I3 transfected lysate ( 35.5 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TP53I3 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TP53I3
Entrez GeneID
9540GeneBank Accession#
NM_004881Protein Accession#
NP_004872Gene Name
TP53I3
Gene Alias
PIG3
Gene Description
tumor protein p53 inducible protein 3
Omim ID
605171Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000116037|p53-induced gene 3 protein|quinone oxidoreductase homolog
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Interactome
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