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Last updated: 2017/2/19

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BAG2 Pre-design Chimera RNAi

  • Catalog # : H00009532-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens BCL2-associated athanogene 2 (BAG2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004282
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9532
  • Gene Name:
  • BAG2
  • Gene Alias:
  • BAG-2,KIAA0576,MGC149462,dJ417I1.2
  • Gene Description:
  • BCL2-associated athanogene 2
  • Gene Summary:
  • BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq
  • Other Designations:
  • BAG-family molecular chaperone regulator-2,OTTHUMP00000016668,dJ417I1.2 (BAG-family molecular chaperone regulator 2)
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