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BAG3 Pre-design Chimera RNAi

  • Catalog # : H00009531-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens BCL2-associated athanogene 3 (BAG3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004281
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9531
  • Gene Name:
  • BAG3
  • Gene Alias:
  • BAG-3,BIS,CAIR-1,MGC104307
  • Gene Description:
  • BCL2-associated athanogene 3
  • Gene Summary:
  • BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq
  • Other Designations:
  • BAG-family molecular chaperone regulator-3,BCL2-binding athanogene 3,Bcl-2-binding protein,OTTHUMP00000020599,docking protein CAIR-1
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