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BAG4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00009530-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BAG4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 50.38
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BAG4 antibody (H00009530-B01) by Western Blots.
    Western Blot
    QC Testing of H00009530-T01
    Lane 1: BAG4 transfected lysate ( 49.6 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00009530-T01
    BAG4 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 9530
  • Gene Name:
  • BAG4
  • Gene Alias:
  • BAG-4,SODD
  • Gene Description:
  • BCL2-associated athanogene 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. [provided by RefSeq
  • Other Designations:
  • BAG-family molecular chaperone regulator-4,silencer of death domains
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