BAG4 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot
Lane 1: BAG4 transfected lysate ( 49.6 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
BAG4 transfected lysate.
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-BAG4 full-length
Host
Human
Theoretical MW (kDa)
50.38
Interspecies Antigen Sequence
Mouse (84); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BAG4 antibody (H00009530-B01) by Western Blots.
Western Blot
Lane 1: BAG4 transfected lysate ( 49.6 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
BAG4 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — BAG4
Entrez GeneID
9530GeneBank Accession#
NM_004874Protein Accession#
NP_004865Gene Name
BAG4
Gene Alias
BAG-4, SODD
Gene Description
BCL2-associated athanogene 4
Omim ID
603884Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. [provided by RefSeq
Other Designations
BAG-family molecular chaperone regulator-4|silencer of death domains
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com