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TBPL1 Pre-design Chimera RNAi

  • Catalog # : H00009519-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens TBP-like 1 (TBPL1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004865
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9519
  • Gene Name:
  • TBPL1
  • Gene Alias:
  • MGC:8389,MGC:9620,STUD,TLF,TLP,TRF2
  • Gene Description:
  • TBP-like 1
  • Gene Summary:
  • Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes. [provided by RefSeq
  • Other Designations:
  • 21-kDA TBP-like protein,OTTHUMP00000017240,TATA box binding protein-related factor 2,TBP-like protein,TBP-related factor 2,second TBP of unique DNA
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