TBPL1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TBPL1 full-length ORF ( AAH17559, 1 a.a. - 186 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.20
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TBPL1
Entrez GeneID
9519GeneBank Accession#
BC017559Protein Accession#
AAH17559Gene Name
TBPL1
Gene Alias
MGC:8389, MGC:9620, STUD, TLF, TLP, TRF2
Gene Description
TBP-like 1
Omim ID
605521Gene Ontology
HyperlinkGene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes. [provided by RefSeq
Other Designations
21-kDA TBP-like protein|OTTHUMP00000017240|TATA box binding protein-related factor 2|TBP-like protein|TBP-related factor 2|second TBP of unique DNA
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Interactome
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Pathway
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Disease
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