LITAF 293T Cell Transient Overexpression Lysate(Denatured)

Catalog # H00009516-T02

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Size:100 uL
Price: USD $ 247.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
SDS-PAGE Gel
QC Test

SDS-PAGE Gel

LITAF transfected lysate.

Western Blot
QC Test

Western Blot

Lane 1: LITAF transfected lysate ( 17.1 KDa)
Lane 2: Non-transfected lysate.

  • Specification

    Transfected Cell Line

    293T

    Plasmid

    pCMV-LITAF full-length

    Host

    Human

    Theoretical MW (kDa)

    17.1

    Interspecies Antigen Sequence

    Mouse (85); Rat (86)

    Quality Control Testing

    Transient overexpression cell lysate was tested with Anti-LITAF antibody (H00009516-D01) by Western Blots.

    SDS-PAGE Gel

    LITAF transfected lysate.

    Western Blot

    Lane 1: LITAF transfected lysate ( 17.1 KDa)
    Lane 2: Non-transfected lysate.

    Storage Buffer

    1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot

  • Gene Info — LITAF

    Entrez GeneID

    9516

    GeneBank Accession#

    NM_004862.2

    Protein Accession#

    NP_004853.2

    Gene Name

    LITAF

    Gene Alias

    FLJ38636, MGC116698, MGC116700, MGC116701, MGC125274, MGC125275, MGC125276, PIG7, SIMPLE, TP53I7

    Gene Description

    lipopolysaccharide-induced TNF factor

    Omim ID

    601098 603795

    Gene Ontology

    Hyperlink

    Gene Summary

    Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq

    Other Designations

    LPS-induced TNF-alpha factor|lipopolysaccharide-induced TNF-alpha factor|lipopolysaccharide-induced tumor necrosis factor-alpha factor|p53-induced gene 7 protein|small integral membrane protein of lysosome/late endosome|tumor protein p53 inducible protein

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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