GAL3ST1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GAL3ST1 protein.
Immunogen
GAL3ST1 (AAH14649.1, 1 a.a. ~ 423 a.a) full-length human protein.
Sequence
MLPPQKKPWESMAKGLVLGALFTSFLLLMYSYAVPPLHAGLASTTPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTFFARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPVVPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHILEVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAWNMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDEAMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWVTKLWKFIRDFLRW
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (84)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GAL3ST1 expression in transfected 293T cell line (H00009514-T01) by GAL3ST1 MaxPab polyclonal antibody.
Lane1:GAL3ST1 transfected lysate(46.53 KDa).
Lane2:Non-transfected lysate.
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Gene Info — GAL3ST1
Entrez GeneID
9514GeneBank Accession#
BC014649.1Protein Accession#
AAH14649.1Gene Name
GAL3ST1
Gene Alias
CST
Gene Description
galactose-3-O-sulfotransferase 1
Omim ID
602300Gene Ontology
HyperlinkGene Summary
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq
Other Designations
GalCer sulfotransferase|cerebroside (3'-phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase
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Interactome
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Pathway
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Publication Reference
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Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism.
Guo R, Hu X, Yamada Y, Harada M, Nakajima T, Kashihara T, Yamada M, Aoyama T, Kamijo Y.
Hypertension Research 2018 Dec; [Epub].
Application:WB-Ti, Mouse, Mouse livers.
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Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice.
Lu Y, Harada M, Kamijo Y, Nakajima T, Tanaka N, Sugiyama E, Kyogashima M, Gonzalez FJ, Aoyama T.
Archives of Toxicology 2018 Oct; [Epub].
Application:WB-Ti, Mouse, Mouse livers.
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Acute kidney injury induced by protein-overload nephropathy down-regulates gene expression of hepatic cerebroside sulfotransferase in mice, resulting in reduction of liver and serum sulfatides.
Zhang X, Nakajima T, Kamijo Y, Li G, Hu R, Kannagi R, Kyogashima M, Aoyama T, Hara A.
Biochemical and Biophysical Research Communications 2009 Dec; 390(4):1382.
Application:WB, Mouse, Liver, Kidney.
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Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism.
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