ADAMTS2 monoclonal antibody (M03), clone 7G3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ADAMTS2.
Immunogen
ADAMTS2 (NP_055059, 1112 a.a. ~ 1210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KHNDIDVFMPTLPVPTVAMEVRPSPSTPLEVPLNASSTNATEDHPETNAVDEPYKIHGLEDEVQPPNLIPRRPSPYEKTRNQRIQELIDEMRKKEMLGK
Host
Mouse
Reactivity
Human, Rat
Interspecies Antigen Sequence
Mouse (88); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADAMTS2 monoclonal antibody (M03), clone 7G3 Western Blot analysis of ADAMTS2 expression in PC-12 ( Cat # L012V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADAMTS2 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — ADAMTS2
Entrez GeneID
9509GeneBank Accession#
NM_014244Protein Accession#
NP_055059Gene Name
ADAMTS2
Gene Alias
ADAM-TS2, ADAMTS-3, NPI, PCINP, PCPNI, hPCPNI
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2|procollagen I N-proteinase|procollagen N-endopeptidase
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