ADAMTS3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ADAMTS3 partial ORF ( NP_055058.1, 1048 a.a. - 1128 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ESCSKRSSTLPPPYLLEAAETHDDVISNPSDLPRSLVMPTSLVPYHSETPAKKMSLSSISSVGGPNAYAAFRPNSKPDGAN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.65
Interspecies Antigen Sequence
Mouse (68); Rat (22)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ADAMTS3
Entrez GeneID
9508GeneBank Accession#
NM_014243Protein Accession#
NP_055058.1Gene Name
ADAMTS3
Gene Alias
ADAMTS-4, KIAA0366
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 3
Omim ID
605011Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3|zinc metalloendopeptidase
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Interactome
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Disease
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