ADAMTS3 monoclonal antibody (M10), clone 1H8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ADAMTS3.
Immunogen
ADAMTS3 (NP_055058.1, 1048 a.a. ~ 1128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ESCSKRSSTLPPPYLLEAAETHDDVISNPSDLPRSLVMPTSLVPYHSETPAKKMSLSSISSVGGPNAYAAFRPNSKPDGAN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (22)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.65 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADAMTS3 monoclonal antibody (M10), clone 1H8. Western Blot analysis of ADAMTS3 expression in Jurkat.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADAMTS3 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — ADAMTS3
Entrez GeneID
9508GeneBank Accession#
NM_014243Protein Accession#
NP_055058.1Gene Name
ADAMTS3
Gene Alias
ADAMTS-4, KIAA0366
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 3
Omim ID
605011Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3|zinc metalloendopeptidase
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Interactome
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Disease
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