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ADAMTS4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00009507-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-ADAMTS4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 36
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-ADAMTS4 antibody (H00009507-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00009507-T01
    ADAMTS4 transfected lysate.
    Western Blot
    QC Testing of H00009507-T01
    Lane 1: ADAMTS4 transfected lysate ( 36 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 9507
  • Protein Accession#:
  • -
  • Gene Name:
  • ADAMTS4
  • Gene Alias:
  • ADAMTS-2,ADAMTS-4,ADMP-1,KIAA0688
  • Gene Description:
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • Gene Summary:
  • This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032249,a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4,aggrecanase-1
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