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ADAMTS4 Pre-design Chimera RNAi

  • Catalog # : H00009507-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005099
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9507
  • Gene Name:
  • ADAMTS4
  • Gene Alias:
  • ADAMTS-2,ADAMTS-4,ADMP-1,KIAA0688
  • Gene Description:
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • Gene Summary:
  • This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032249,a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4,aggrecanase-1
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