ADAMTS4 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of ADAMTS4 expression in transfected 293T cell line (H00009507-T01) by ADAMTS4 MaxPab polyclonal antibody.
Lane 1: ADAMTS4 transfected lysate(37.29 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ADAMTS4 protein.
Immunogen
ADAMTS4 (AAH30812.1, 1 a.a. ~ 339 a.a) full-length human protein.
Sequence
MSQTGSHPGRGLAGRWLWGAQPCLLLPIVPLSWLVWLLLLLLASLLPSARLASPLPREEEIVFPEKLNGSVLPGSGAPARLLCRLQAFGETLLLELEQDSGVQVEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGAELHLQPLEGGTPNSAGGPGAHILRRKSPASGQGPMCNVKAPLGSPSPRPRRAKRFASLSRFVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQVRPQSAPQAMHCTILRSATT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (84)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ADAMTS4 expression in transfected 293T cell line (H00009507-T01) by ADAMTS4 MaxPab polyclonal antibody.
Lane 1: ADAMTS4 transfected lysate(37.29 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ADAMTS4
Entrez GeneID
9507GeneBank Accession#
BC030812.1Protein Accession#
AAH30812.1Gene Name
ADAMTS4
Gene Alias
ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 4
Omim ID
603876Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq
Other Designations
OTTHUMP00000032249|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4|aggrecanase-1
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Interactome
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Disease
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