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Last updated: 2016/10/23
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ADAMTS4 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00009507-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human ADAMTS4 protein.
  • Immunogen:
  • ADAMTS4 (AAH30812.1, 1 a.a. ~ 339 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of ADAMTS4 expression in transfected 293T cell line (H00009507-T01) by ADAMTS4 MaxPab polyclonal antibody.

    Lane 1: ADAMTS4 transfected lysate(37.29 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9507
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • Gene Summary:
  • This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032249,a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4,aggrecanase-1
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