IL27RA monoclonal antibody (M01), clone 8G9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IL27RA.
Immunogen
IL27RA (NP_004834, 33 a.a. ~ 132 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QGSAGPLQCYGVGPLGDLNCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFVNLETQMKPNAPR
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — IL27RA
Entrez GeneID
9466GeneBank Accession#
NM_004843Protein Accession#
NP_004834Gene Name
IL27RA
Gene Alias
CRL1, IL27R, TCCR, WSX1, zcytor1
Gene Description
interleukin 27 receptor, alpha
Omim ID
605350Gene Ontology
HyperlinkGene Summary
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq
Other Designations
T-cell cytokine receptor type 1|class I cytokine receptor
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Interactome
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Disease
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