PICK1 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (97)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of PICK1 transfected lysate using rabbit polyclonal anti-PICK1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-PICK1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-PICK1 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-PICK1 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — PICK1
Entrez GeneID
9463Gene Name
PICK1
Gene Alias
MGC15204, PICK, PRKCABP
Gene Description
protein interacting with PRKCA 1
Omim ID
605926Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028509|PRKCA-binding protein|protein interacting with C kinase 1|protein kinase C, alpha binding protein
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Interactome
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Disease
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